Symposium lectures on-line

Most of the lectures of the Symposium were published on-line. You can find the video presentations at the top of each lecture abstract. We hope to complete the whole on-line program in the near feature.

Pictures of Semmelweis Symposium 2008

You can find the pictures of all the three days of Semmelweis Symposium 2008 here.

Lecture of Prof. Sándor Kovács

You can find the whole video-presentation of Prof. Sándor Kovács at "Lectures" on the following page.

Summary

More than 500 participants from 20 countries attended Semmelweis Symposium 2008. You can find a detailed summary of the event here. A summary of press echo in the Hungarian media you can find here.

Poster abstracts

You can find the poster abstracts of Semmelweis Symposium 2008 here.

Scientific Program - printable version

You can download the printable version of the Scientific Program here.

Cardiovascular pharmacogenomics course

According to the program of Semmelweis Symposium, Peter Pokreisz (Katholieke Universiteit Leuven, Belgium) will give a lecture (in Hungarian) on cGMP regulatory mechanisms in cardiology at 18:00 Wednesday, 26 November.

Abstract submission period extended

The deadline for abstract submission was extended until 18 November 2008. More detailes on the Abstract submission form.

On-line registration

Participation in the program of Semmelweis Symposium 2008 is free.
However, completion the on-line registration form is required to attend the Symposium.

Abstract submission for poster presentation

Abstracts for poster presentation are welcome to the Semmelweis Symposium. Deadline for abstract submission  is 15 November. More detailes on the Abstract Submission Form.

PhD course registration

Semmelweis Symposium 2008 was accredited by the School of Doctoral Studies of Semmelweis University. Students attending all the three days of the Symposium will get 2 PhD credits.

OFTEX registration

Semmelweis Symposium 2008 was registred to the OFTEX system. Colleagues attending all the three days of the Symposium will get 20 OFTEX credits. For detailed information look for SE-TK/2008-07/00383 at www.oftex.hu .

Final program

The final program of the Symposium has been completed. For detailes visit to the Scientific Program pages.

Current trends in Cardiology

This year cardiology is in the focus of Semmelweis Symposium. The members of the Heart Center take the opportunity to kindly invite you to this event.

Nitric oxide (NO), as a powerful vasodilator agent is of primary importance in the vasoregulation of the newborn. We hypothesized that carrier state of genetic polymorphisms with a decreased function of endothelial NO synthase (eNOS) and thus with low NO levels may be associated with an altered susceptibility to cardiac failure (CF) in preterm infants. We enrolled 120 preterm infants born with birth weight ≤1500 grams. Their eNOS genotype was related to the occurrence of CF during the first postnatal week (n = 37). We also analyzed the impact of genotype on CF risk in a subgroup of septic-free patients. Carrier state of 27bp b/a polymorphism presented a 1.53 (1.071 – 2.184) risk ratio (RR) to CF in the whole group of infants; the association remained significant after the adjustment of CF risk factors. In septic free patients, each genetic variant (27bp b/a, T786C and G+894T) was associated with increased risk of CF (RR values (95% CI): 1.823 (1.200- 2.770), 1.252 (1.014 – 1.547) and 1.606 (0.901 – 2.861), respectively). Our results clearly indicate that low NO producing genotype increases the risk of CF in VLBW infants. This result contradicts to the general assumptions that lower than normal NO may increase blood pressure, but is in line with other observations suggesting discrepancies between NO action and blood pressure in human neonates. Further studies are required to elucidate the possible mechanisms underlying the link between eNOS genotype and blood pressure regulation in preterm infants.