INFORMATION

Date: 27-29 November 2008

Fax: +36-1-4586842
Email: symposium@kardio.sote.hu
Visit the homepage of the Heart Center.
CONFERENCE NEWS
Symposium lectures on-line
20 February, 2009
Most of the lectures of the Symposium were published on-line. You can find the video presentations at the top of each lecture abstract. We hope to complete the whole on-line program in the near feature.
Pictures of Semmelweis Symposium 2008
1 January, 2009
You can find the pictures of all the three days of Semmelweis Symposium 2008 here.
Lecture of Prof. Sándor Kovács
31 December, 2008
You can find the whole video-presentation of Prof. Sándor Kovács at "Lectures" on the following page.
Summary
30 November, 2008
More than 500 participants from 20 countries attended Semmelweis Symposium 2008. You can find a detailed summary of the event here. A summary of press echo in the Hungarian media you can find here.
Poster abstracts
27 November, 2008
You can find the poster abstracts of Semmelweis Symposium 2008 here.
Scientific Program - printable version
23 November, 2008
You can download the printable version of the Scientific Program here.
Cardiovascular pharmacogenomics course
22 November, 2008
According to the program of Semmelweis Symposium, Peter Pokreisz (Katholieke Universiteit Leuven, Belgium) will give a lecture (in Hungarian) on cGMP regulatory mechanisms in cardiology at 18:00 Wednesday, 26 November.
Abstract submission period extended
14 November 2008
The deadline for abstract submission was extended until 18 November 2008. More detailes on the Abstract submission form.
On-line registration
4 November. 2008
Participation in the program of Semmelweis Symposium 2008 is free.
However, completion the on-line registration form is required to attend the Symposium.
Abstract submission for poster presentation
3 November, 2008
Abstracts for poster presentation are welcome to the Semmelweis Symposium. Deadline for abstract submission  is 15 November. More detailes on the Abstract Submission Form.
PhD course registration
2 November, 2008
Semmelweis Symposium 2008 was accredited by the School of Doctoral Studies of Semmelweis University. Students attending all the three days of the Symposium will get 2 PhD credits.
OFTEX registration
2 November, 2008
Semmelweis Symposium 2008 was registred to the OFTEX system. Colleagues attending all the three days of the Symposium will get 20 OFTEX credits. For detailed information look for SE-TK/2008-07/00383 at www.oftex.hu .
Final program
30 October, 2008
The final program of the Symposium has been completed. For detailes visit to the Scientific Program pages.
Current trends in Cardiology
18 August. 2008
This year cardiology is in the focus of Semmelweis Symposium. The members of the Heart Center take the opportunity to kindly invite you to this event.
Scientific Program | Pictures | Lectures | Posters | Location

Novel non-lipid markers of cardiovascular disease


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Prof. Dr. Zoltán Prohászka got MD diploma at the University Medical School in Budapest in 1995. Since that time he has been working in the 3rd Department of Medicine of Semmelweis University. In 1999 onwards Research Fellow in the Research Group Inflammation Biology and Immunogenomics, Hungarian Academy of Sciences. In 2000 he defends Ph.D. thesis an in 2006 defends D.Sc. thesis. In 1997 he received Selye-Award of the Cell Stress Society International. From 2007 Secretary General of the Hungarian Society for Immunology. Between 1999–2002 Bolyai János Research Fellow (supported by Hungarian Academy of Sciences). Main topicsof his scientific interest: complement research, AIDS research, atherosclerosis research, heat-shock proteins. Professor Prohászka published more than 100 papersin peer-reviewed journals. Professor Prohászka was the organizer of the XIV. Semmelweis Symposium “Inflammatory Mechanisms in Atherosclerosis: A critical appraisal” in 2005.

Abstract

It is well accepted, that atherosclerosis is an inflammatory disease. The inflammatory mechanisms are present in all phases of plaque development – from endothelial dysfunction to plaque rupture. Several markers of ongoing inflammation may be elevated in the affected patients. Some of the best-studied markers belong to the acute phase proteins (as C-reactive protein), cytokines (as IL-6) and the complement system (C3, C1-inhibitor).The complement system is a part of the innate immune system, which plays essential role in the defense against microbial infections, clearance of immune complexes and bridging innate and adaptive immunity. Moreover, it is well known that inappropriate activation of complement contributes to the pathophysiology of several diseases. It has been shown, that complement activation plays an important role in the atherosclerotic process also. Based on our results, complement proteins are associated with the presence and with the progression of atherosclerosis. Complement proteins are able to predict new vascular events in patients following coronary artery bypass graft surgery or restenosis following carotid endarterectomy. Moreover, the degree of complement activation predicts functional disability in patients with ischemic stroke.
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